Transitioning to a future that is both digital and sustainable provides an opportunity for Europe to become a leader in the global economy while ensuring humans and the environment are firmly at the centre of technological developments. To this end, the EU-funded HiPEAC project aims to strengthen European leadership in the global data economy and accelerate the digital and green transitions through human-centred innovations. The project will take two approaches: first, it will guide the research and innovation of key enabling technologies as part of comprehensive value chains through roadmapping and alignment activities; second, it will develop the European computing ecosystem that underpins digital transformation through networking and capacity-building activities.